Page Last Updated: 12 October 2013
Jesse Gelsinger was an 18-year-old subject in a gene transfer research study. Affected by Ornithine Transcarbamylase (OTC) deficiency he was comparatively healthy and his symptoms manageable. In 1999 researchers transferred some genes using an adenovirus which triggered a deadly immune response and he subsequently died. It raised questions about risk versus benefit.
Source: Encyclopedia of Bioethics
Ethics, Politics & Culture in Medical History 